Osteochondritis dissecans | Genetic and Rare Diseases …
Osteochondritis dissecans – Symptoms and causes – Mayo Clinic, 19 rows · 2/8/2015 · In some families, osteochondritis dissecans is caused by changes (mutations) in the ACAN gene. In these cases, which are referred to as familial osteochondritis dissecans, the condition generally affects multiple joints and is also associated with short stature and early-onset osteoarthritis.
Familial osteochondritis dissecans is a condition that affects the joints and is associated with abnormal cartilage. Cartilage is a tough but flexible tissue that covers the ends of the bones at joints and is also part of the developing skeleton.
Familial osteochondritis dissecans is caused by inherited mutations (changes) to the ACAN gene, which is the source of a cartilage-building protein called aggrecan. Because of the mutation, the protein cannot build cartilage like it should, so the cartilage is weak and disorganized.
2/8/2015 · In some families, osteochondritis dissecans is caused by changes ( mutations) in the ACAN gene. In these cases, which are referred to as familial osteochondritis dissecans, the condition generally affects multiple joints and is also associated with short stature and early-onset osteoarthritis.
MalaCards based summary : Familial Osteochondritis Dissecans, also known as osteochondritis dissecans, short stature , and early-onset osteoarthritis, is related to osteochondritis dissecans and obsessive- compulsive disorder, and has symptoms including [malacards.org] Neurologic. Excitement.
In some families, osteochondritis dissecans is caused by changes (mutations) in the ACAN gene. In these cases, which are referred to as familial osteochondritis dissecans, the condition generally affects multiple joints and is also associated with short stature and early-onset osteoarthritis.
8/15/2018 · Osteochondritis dissecans is a joint condition whereby a variable amount of bone and its adjacent cartilage loses its blood supply. Osteochondritis dissecans causes irregularity and fragility of affected cartilage. As a result, it is possible for portions of cartilage to become lodged within the joint, leading to limitation in motion.
Osteokondritis dissekans merupakan sebuah penyakit pada sendi di mana sebagian kecil dari tulang mulai memisah dari daerah sekitarnya dikarenakan kekurangan aliran darah.Penyakit ini paling sering ditemui pada anak-anak dan remaja.Sendi yang paling sering terkena adalah lutut, pergelangan kaki dan siku.Penyakit ini biasanya hanya terdapat pada satu sendi.
